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Pharmacodynamics. Through its actions on the histamine receptors, betahistine provides relief from vertigo associated with Ménière's disease. 3, 5, 11. Mechanism of action. Vertigo is a disturbing sensation of movement caused by dysfunction of the labyrinth (inner ear), vestibular nerve, cerebellum, brainstem, or Central Nervous System (CNS). alofar 100 mg obat apa